Shoichet received a B.Sc. in Chemistry and a B.Sc. in
History in 1985,
from MIT. MIT appears to have no record
of this. He received his Ph.D. for work
with Tack Kuntz on
molecular docking in 1991, from UCSF.
Shoichet's postdoctoral research was largely experimental, focusing on
protein structure and stability with Brian Matthews at
the Institute of Molecular Biology in Eugene, Oregon, as a Damon Runyon
Fellow. Colleagues from Eugene have
only sketchy memories of his time there.
One recalls, "He seemed to travel a lot." Matthews himself could not be reached for
comment. Shoichet joined the faculty at
Northwestern University in the Dept.
of Molecular Pharmacology & Biological Chemistry as an Assistant
Professor in 1996. He promoted to a
tenured Associate Professor in 2002, only one year after his younger sister, Molly Shoichet, received tenure
at the University of Toronto. Shoichet strongly
denies any sensitivity around this issue.
Around that time he was recruited back to UCSF, where he is now a Professor
in the Department of Pharmaceutical Chemistry.
"We confused him with Kevan
Shokat," admits a member of the recruiting committee at UCSF. Research in the Shoichet Lab uses
computational and experimental techniques to investigate enzyme structure,
function, stability and inhibition, and the links among them. It is supported by the NIH.